Due to the reduced immunity, experts believe that an immunization booster is now needed. According to preliminary data, three side effects were reported when the fourth dose was given.
The coronavirus vaccine has had a positive effect on outbreaks, reducing hospital admissions and mortality rates across the country. However, reduced immunity has led to further obstacles to vaccine promotion.
Thousands of vulnerable people will be brought forward for top-ups this week in an effort to combat the decline in immunity.
Some negative effects have been identified based on data obtained from Israeli research earlier this year.
According to preliminary data released in January, the side effects of the second booster dose of the Pfizer BioNTech vaccine are mild.
The results were obtained during a January study at Sheba Medical Center, which gave its staff a second booster shot in the wake of a statewide outbreak of Omicron infection.
About 150 medical workers received a fourth dose of the Pfizer and BioNTech vaccines when their antibody levels dropped dramatically four to five months ago after receiving their third dose.
According to the researchers, the negative effects of the fourth and third doses of the vaccine were not significantly different.
According to Reuters, the medical center noted that adverse effects included discomfort, fever and headache.
In addition, an Israeli trial conducted by Sheba Medical Center in January indicated that the number of antibodies increased fivefold one week after the administration of the fourth booster dose.
Body aches, headaches and fatigue are the most common adverse effects reported after the third dose, some people also report cold and swollen lymph nodes.
Such side effects, according to scientists, are a sign that the immune system is reacting to the shots.
In January, Israeli Prime Minister Naftali Bennett told reporters: “One week after the fourth dose, we know for sure that the fourth dose is safe.
“The second piece of news [is] We know that one week after the fourth dose, we see a fivefold increase in the number of antibodies in the vaccinated person.
“This probably means a significant increase against infections and hospitalization and severe symptoms.”
Recently, the Medical Center published a report in the New England Journal of Medicine detailing the effectiveness of a fourth dose, the first for the organization.
The study confirmed that the 4th shot “did not cause significant adverse events in most recipients, despite triggering mild systemic and local symptoms”.
However, the study authors claim that those who have been vaccinated and boosted with Pfizer-BioNTech shots may only be offered a “marginal benefit” of being given a fourth round.
They added: “Our team was too small to accurately determine the effectiveness of the vaccine.
“However, within the broad confidence interval of our estimates, the effectiveness of the vaccine against notable diseases was at most 65 percent.”
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You read: Three side effects can be expected from a Pfizer second booster shot